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Progenesis Main Focus

Progenesis is a San Diego-based company founded in 2015 that develops and offers non-invasive genetic tests for patients on their family planning journey. We offer a variety of services that can be customized to meet the needs of every patient we serve. The Progenesis team is a motivated group of genetic specialists, researchers, laboratory professionals, and analysts who are passionate about improving our patients' lives. As pioneers in genetic screening technologies, our scientists are constantly pursuing research initiatives to advance our services and expand our understanding of human genetics.
Address: 4150 Regents Park Row Suite 245 La Jolla, CA 92037

Email: [email protected]
Phone: (858) 257-2122
Fax: (858) 469-8600

Essential Panel

ACMG and ACOG Recommended Conditions

Avenir® Essential

Neurologic, Cognitive: affecting brain, eyes, or spinal cord, potentially impacting intellectual ability or behavior.

Metabolic, Endocrine: affecting gastrointestinal tract, liver, kidneys, endocrine glands, or reproductive organs.

Circulatory, Respiratory: affecting lungs, heart, blood, or immune system.

Skin, Bones, Muscle: affecting skin, hair, bones, or muscles.

Shortened Life Expectancy: Increased risk of mortality in infancy or childhood. Decreased lifespan resulting from life-threatening complications.

Treatments Available: Most genetic disorders have no cure, but treatments are typically specific to the patient and focus on reducing or managing symptoms.

Our Essential panel screens for disorders recommended by the American College of Medical Genetics and Genomics (ACMG) and the American Congress of Obstetricians and Gynecologists (ACOG).

ACMG is a society of health professionals that strives to establish the best clinical and laboratory practices pertaining to genetic initiatives. In July 2013, ACMG published a list of recommendations for reporting findings in clinical DNA. With the goal of preventing morbidity and mortality, the list is comprised of inherited cancers as well as autosomal and X-linked diseases. See the full list and read more about how these conditions and genes were selected here. Each of these clinically relevant disorders are available on our customizable Avenir® panels. Inherited cancers on the ACMG list are tested on our Cancer Panel, while the remaining autosomal and X-linked disorders are screened on Avenir® Essential.

ACOG is an organization of medical specialists dedicated to the improvement of women’s health. In March 2017, ACOG released a Committee Opinion regarding carrier screening for genetic conditions. Detailed recommendations are available for specific conditions that are more common in the population. These include spinal muscular atrophy, Tay-Sachs disease, cystic fibrosis, and various hemoglobinopathies. See the full discussion about these diseases here. ACOG also suggests expanded genetic screening for individuals of Ashkenazi Jewish heritage; these conditions are tested on our Comprehensive panel.

By synthesizing the recommendations of these two groups, we have developed a genetic panel that screens for 23 of the most medically relevant genetic disorders in the United States.